"Defend Ned" is a mission objective in Sequence 5 / Memory: Research and Development
Walkthrough[edit]
Look back toward the train that you were on at the start of the mission. If you completed the optional objective then there is very little you need to do her.
Wait for the train to get close enough then jump over to it.
Head onto the pair of cars where the Rooks and Ned are. Just fend off whatever Blighters are there.