"Follow Desmond's barks to find the dognapper" is a mission objective in Sequence 7 / Memory: Driving Mrs Disraeli
Walkthrough[edit]
Head out to the West from the Pub. Turn to the North shortly after that to keep up.
When you reach the next intersection, slow a moment and use Eagle Vision to quickly get your bearings. Take the left hand turn here and head to the South.
Go to the next locate marker that is ahead of you. Once again, use Eagle Vision to quickly location where the culprit went. Turn to the right when you reach this marker, going to the West once again.
Keep going to the West to reach the next locate marker. It will be very quick to find the one after that.
Make your way to the Northwest as you quickly get through the last bits of Devil's Acre. Get to the Wall and continue to the East.
The next locate marker is just ahead of you. Keep going to the East and under the tracks in front of you.
Make your way around the fences in front of you. Just make it to this last marker to trigger a cutscene where Jacob gets Desmond back.
A very amusing scene is playing out when Jacob makes it back to the pub with Desmond. Mary Ann is talking with a number of Blighters about their families.