“Destroy your enemies.”
“Clear the room” is an objective in the mission The Blighted Chalice in Destiny: The Taken King
To get through the door you will need to destroy the Hive and Taken in this room, collect the Tomb Husk and bring it to the 3 Hive Runes. You will need to fight through a wave of enemies to get just one Husk. It will appear in a number of places throughout this portion of the strike.
The first husk appears in the back middle of the area. You can find it about where Malok appeared.
After the first Husk goes in, more Hive will start appearing from the doors into the area.
The second tomb husk appears in the upper right-hand ledge from where you began the strike.
More Thrall will appear and start rushing your location. There will be more variety in this wave so be ready to deal with them.
Go to the lower back left corner from where you came in. Grab the Tomb Husk and bring it to the door. It will finally open and let you inside.