Valery Barstow was going to be the Overseer of Vault 88. However, the bombs fell only a little after ground was broken on the construction of the Vault. The blasts turned her into a Ghoul. It was her loyalty to Vault-Tec and their cause that kept her sane through the intervening 200 years.
During the 200 years she has been trapped inside the uncompleted Vault, she has been preparing a number of Experiments that Vault-Tec selected for the Vault. She will recruit the Sole Survivor to aid her with the undertaking of running the experiments.
Likes and Dislikes
Valery will like it when you keep to the guidelines that were laid out by Vault-Tec and herself.
If you follow the more humane options, she will eventually leave the Vault in frustration.