A D10 in the Binding of Isaac: Rebirth (BOIR)
D10: Reroll enemies

The D10 is a Active item in The Binding of Isaac: Rebirth (TBOIR)


  • Activate to "reroll" all monsters in the room, replacing each with a different monster.


Strategy Guide/Tips

  • You could get easiers monsters but you could also get harder monsters and even champions
  • You can get enemies from any floor. This is dangerous if you are rerolling at an early floor and are not equipped to deal with harder enemies.
  • You can't reroll bosses, but you can reroll the monsters that the boss spawned


  • Flying enemies can be replaced with non-flying enemies and become stuck behind a rock, making the room impossible to clear


  • The D10 is a 10-sided die, frequently use in games of Dungeons & Dragons