A Devil Room in the Binding of Isaac: Rebirth (BOIR)
Isaac being teleported to a Devil Room after opening a Red Chest

The Devil Room is a type of Room in The Binding of Isaac: Rebirth (TBOIR)

In this room, you can make a deal with the Devil

There will be two items which you can buy for a certain amount of Heart Containers. Basically you are sacrificing max health to get an item.

How to find a Devil Room

  • Chance to appear after defeating a Boss
  • Use Joker Card
  • Chance of being teleported to Devil Room after opening Red Chest

Strategy Guide/Tips

  • A Pentagram increases the chance of a Devil Room to appear on the floor.