The Jelly's Share Safe is the first safe you find in the game Dishonored
Contents
Safe Location
Dunwall Sewers past the Dunwall Sewer Gate
Mission
Dishonored - Fugitive (First Mission)
Message Displayed
Jelly's Share Safe Combination Needed
Safe Combination
Safe combination is: 451[1]
If that doesn't work, try 632
If you read the note called Jelly's Share it hints to look for code in Whiskey. There is a section near the safe where it says "Whiskey" and there is a shelves with bottles on it. If you clear the bottles from the shelves above the whiskey box, behind them it says "451" (Since sewers are dark this can be hard to see, try upping your brightness if you can't see the combo)
Additionally, a LOT of games (eg. System Shock, Deus Ex 1, Bioshock, Sanitarium etc.) use this combination for the first combination lock/keypad, so it is also possible to guess it.