The Red Prince suffering from a disease after talking to Mona at the Fort Joy Ghetto in Divinity Original Sin II (D:OS2)

Diseased is a Status Effect in Divinity: Original Sin 2


Diseased lowers your character's elemental and poison resistances, as well as decreasing maximum health.


  • Maximum Vitality is decreased
  • Cured by Magic Shell, Bless
  • Fire Resistance: -25%
  • Earth Resistance: -25%
  • Water Resistance: -25%
  • Air Resistance: -25%
  • Poison Resistance: -25%



Strategy Guide/Tips[edit]

  • Certain spells and weapons may inflict disease on the target.
  • Eating a Body Part without the "Corpse Eater" talent can give the character a disease.
  • Speaking to certain diseased characters (such as Mona in Fort Joy) can also cause you to become diseased.